Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor–Related Protein 6

Connective tissue growth factor (CTGF), a matrix-associated protein with four distinct cytokine binding domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregulated in fibroblasts and myofibroblasts in disease. Here, we investigated the role of CTGF in fibrogeni...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Johnson, Bryce G., Ren, Shuyu, Karaca, Gamze, Gomez, Ivan G., Fligny, Cécile, Smith, Benjamin, Ergun, Ayla, Locke, George, Gao, Benbo, Hayes, Sebastian, MacDonnell, Scott, Duffield, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461793/
https://ncbi.nlm.nih.gov/pubmed/28130402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080826
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados