Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor–Related Protein 6

Connective tissue growth factor (CTGF), a matrix-associated protein with four distinct cytokine binding domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregulated in fibroblasts and myofibroblasts in disease. Here, we investigated the role of CTGF in fibrogeni...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Soc Nephrol
मुख्य लेखकों: Johnson, Bryce G., Ren, Shuyu, Karaca, Gamze, Gomez, Ivan G., Fligny, Cécile, Smith, Benjamin, Ergun, Ayla, Locke, George, Gao, Benbo, Hayes, Sebastian, MacDonnell, Scott, Duffield, Jeremy S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Nephrology 2017
विषय:
Basic Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461793/
https://ncbi.nlm.nih.gov/pubmed/28130402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080826
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