Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury

Ischemia-reperfusion injury (IRI) is a leading cause of AKI. This common clinical complication lacks effective therapies and can lead to the development of CKD. The αvβ5 integrin may have an important role in acute injury, including septic shock and acute lung injury. To examine its function in AKI,...

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Bibliografische gegevens
Gepubliceerd in:J Am Soc Nephrol
Hoofdauteurs: McCurley, Amy, Alimperti, Stella, Campos-Bilderback, Silvia B., Sandoval, Ruben M., Calvino, Jenna E., Reynolds, Taylor L., Quigley, Catherine, Mugford, Joshua W., Polacheck, William J., Gomez, Ivan G., Dovey, Jennifer, Marsh, Graham, Huang, Angela, Qian, Fang, Weinreb, Paul H., Dolinski, Brian M., Moore, Shaun, Duffield, Jeremy S., Chen, Christopher S., Molitoris, Bruce A., Violette, Shelia M., Crackower, Michael A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2017
Onderwerpen:
Basic Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461783/
https://ncbi.nlm.nih.gov/pubmed/28062569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020200
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