Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury

Ischemia-reperfusion injury (IRI) is a leading cause of AKI. This common clinical complication lacks effective therapies and can lead to the development of CKD. The αvβ5 integrin may have an important role in acute injury, including septic shock and acute lung injury. To examine its function in AKI,...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: McCurley, Amy, Alimperti, Stella, Campos-Bilderback, Silvia B., Sandoval, Ruben M., Calvino, Jenna E., Reynolds, Taylor L., Quigley, Catherine, Mugford, Joshua W., Polacheck, William J., Gomez, Ivan G., Dovey, Jennifer, Marsh, Graham, Huang, Angela, Qian, Fang, Weinreb, Paul H., Dolinski, Brian M., Moore, Shaun, Duffield, Jeremy S., Chen, Christopher S., Molitoris, Bruce A., Violette, Shelia M., Crackower, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461783/
https://ncbi.nlm.nih.gov/pubmed/28062569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020200
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