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The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis
Rev1 is a deoxycytidyl transferase associated with DNA translesion synthesis (TLS). In addition to its catalytic domain, Rev1 possesses a so-called BRCA1 C-terminal (BRCT) domain. Here, we describe cells and mice containing a targeted deletion of this domain. Rev1(B/B) mice are healthy, fertile and...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546167/ https://ncbi.nlm.nih.gov/pubmed/15653636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki189 |
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