Inhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZL

The tRNA 3′-processing endoribonuclease (tRNase Z or 3′ tRNase; EC 3.1.26.11) is an essential enzyme that removes the 3′ trailer from pre-tRNA. The long form (tRNase ZL) can cleave a target RNA in vitro at the site directed by an appropriate small-guide RNA (sgRNA). Here, we investigated whether thi...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Habu, Yuichiro, Miyano-Kurosaki, Naoko, Kitano, Michiko, Endo, Yumihiko, Yukita, Masakazu, Ohira, Shigeru, Takaku, Hiroaki, Nashimoto, Masayuki, Takaku, Hiroshi
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2005
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546152/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15647506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gki164
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