Intracellular mRNA cleavage by 3′ tRNase under the direction of 2′-O-methyl RNA heptamers

Mammalian tRNA 3′ processing endoribonuclease (3′-tRNase) can cleave any RNA at any site under the direction of small guide RNA (sgRNA) in vitro. sgRNAs can be as short as heptamers, which are much smaller than small interfering RNAs of ∼21 nt. Together with such flexibility in substrate recognition...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Tamura, Masato, Nashimoto, Chikako, Miyake, Noriko, Daikuhara, Yasushi, Ochi, Kozo, Nashimoto, Masayuki
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2003
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12888494/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg641
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