Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage

Regulatory T cells (Tregs) restrict overexuberant lymphocyte activation. While close proximity between Tregs and their suppression targets is important for optimal inhibition, and literature indicates that draining lymph nodes (LNs) may serve as a prime location for the suppression, signaling detail...

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Foilsithe in:Front Immunol
Main Authors: Geng, Shuang, Zhong, Yiwei, Zhou, Xiaoyu, Zhao, Gan, Xie, Xiaoping, Pei, Yechun, Liu, Hu, Zhang, Huiyuan, Shi, Yan, Wang, Bin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2017
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461288/
https://ncbi.nlm.nih.gov/pubmed/28638384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00663
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