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Electrostatic engineering of the interface between heavy and light chains promotes antibody Fab fragment production
Monoclonal antibodies and antibody fragments are used for diverse diagnostic and therapeutic applications. We have investigated the secretory production of Fab fragments from insect cells cotransfected with plasmid vectors carrying heavy- and light-chain genes. In the present study, to promote the f...
Gorde:
| Argitaratua izan da: | Cytotechnology |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer Netherlands
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461237/ https://ncbi.nlm.nih.gov/pubmed/26856589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-016-9955-4 |
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