Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes

TRPV4 (transient receptor potential vanilloid 4) channels are Ca(2+)-permeable channels that play a key role in regulating vascular tone. In arterial myocytes, opening of TRPV4 channels creates local increases in Ca(2+) influx, detectable optically as “TRPV4 sparklets.” TRPV4 sparklet activity can b...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Tajada, Sendoa, Moreno, Claudia M., O’Dwyer, Samantha, Woods, Sean, Sato, Daisuke, Navedo, Manuel F., Santana, L. Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460949/
https://ncbi.nlm.nih.gov/pubmed/28507079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611709
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