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AKAP150-mediated TRPV1 sensitization is disrupted by calcium/calmodulin

BACKGROUND: The transient receptor potential vanilloid type1 (TRPV1) is expressed in nociceptive sensory neurons and is sensitive to phosphorylation. A-Kinase Anchoring Protein 79/150 (AKAP150) mediates phosphorylation of TRPV1 by Protein Kinases A and C, modulating channel activity. However, few st...

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Bibliografiska uppgifter
Huvudupphovsmän: Chaudhury, Sraboni, Bal, Manjot, Belugin, Sergei, Shapiro, Mark S, Jeske, Nathaniel A
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113319/
https://ncbi.nlm.nih.gov/pubmed/21569553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-34
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