A carregar...
An Antibody to Notch2 Reverses the Osteopenic Phenotype of Hajdu-Cheney Mutant Male Mice
Notch receptors play a central role in skeletal development and bone remodeling. Hajdu-Cheney syndrome (HCS), a disease characterized by osteoporosis and fractures, is associated with gain-of-NOTCH2 function mutations. To study HCS, we created a mouse model harboring a point 6955C>T mutation in t...
Na minha lista:
| Publicado no: | Endocrinology |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460801/ https://ncbi.nlm.nih.gov/pubmed/28323963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1787 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|