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Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases
Glucocorticoid excess, either endogenous with diseases of the adrenal gland, stress, or aging or when administered for immunosuppression, induces bone and muscle loss, leading to osteopenia and sarcopenia. Muscle weakness increases the propensity for falling, which, combined with the lower bone mass...
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出版年: | Endocrinology |
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主要な著者: | , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Endocrine Society
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460781/ https://ncbi.nlm.nih.gov/pubmed/28359087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1779 |
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