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Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases

Glucocorticoid excess, either endogenous with diseases of the adrenal gland, stress, or aging or when administered for immunosuppression, induces bone and muscle loss, leading to osteopenia and sarcopenia. Muscle weakness increases the propensity for falling, which, combined with the lower bone mass...

詳細記述

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書誌詳細
出版年:Endocrinology
主要な著者: Sato, Amy Y., Richardson, Danielle, Cregor, Meloney, Davis, Hannah M., Au, Ernie D., McAndrews, Kevin, Zimmers, Teresa A., Organ, Jason M., Peacock, Munro, Plotkin, Lilian I., Bellido, Teresita
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460781/
https://ncbi.nlm.nih.gov/pubmed/28359087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1779
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