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PCDH18 is frequently inactivated by promoter methylation in colorectal cancer
Protocadherin18 (PCDH18) was found to be preferentially methylated and inactivated in colorectal cancer (CRC) using bioinformatics tools. However, its biologic role in tumorgenesis remains unclear. Herein, we aimed to elucidate its epigenetic regulation and biological functions in CRC. The methylati...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460281/ https://ncbi.nlm.nih.gov/pubmed/28588296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03133-w |
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