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JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer

PURPOSE: JAM3, an adhesion and transmigration regulatory element, is abundantly expressed in intestinal epithelial cells. However, its expression and function in colorectal cancer (CRC) remain unknown. In this study, we explored its epigenetic mechanism and biological role in CRC. PATIENTS AND METHO...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Zhou, Dan, Tang, Weiwei, Zhang, Yun, An, Han-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441464/
https://ncbi.nlm.nih.gov/pubmed/30988641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S189937
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