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R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

The R2TP/Prefoldin-like (R2TP/PFDL) complex has emerged as a cochaperone complex involved in the assembly of a number of critical protein complexes including snoRNPs, nuclear RNA polymerases and PIKK-containing complexes. Here we report on the use of multiple target affinity purification coupled to...

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Publicat a:Nat Commun
Autors principals: Cloutier, Philippe, Poitras, Christian, Durand, Mathieu, Hekmat, Omid, Fiola-Masson, Émilie, Bouchard, Annie, Faubert, Denis, Chabot, Benoit, Coulombe, Benoit
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460035/
https://ncbi.nlm.nih.gov/pubmed/28561026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15615
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