R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

The R2TP/Prefoldin-like (R2TP/PFDL) complex has emerged as a cochaperone complex involved in the assembly of a number of critical protein complexes including snoRNPs, nuclear RNA polymerases and PIKK-containing complexes. Here we report on the use of multiple target affinity purification coupled to...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Cloutier, Philippe, Poitras, Christian, Durand, Mathieu, Hekmat, Omid, Fiola-Masson, Émilie, Bouchard, Annie, Faubert, Denis, Chabot, Benoit, Coulombe, Benoit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460035/
https://ncbi.nlm.nih.gov/pubmed/28561026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15615
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