High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes

Thirty years of research on gene transcription has uncovered a myriad of factors that regulate, directly or indirectly, the activity of RNA polymerase II (RNAPII) during mRNA synthesis. Yet many regulatory factors remain to be discovered. Using protein affinity purification coupled to mass spectrome...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Cloutier, Philippe, Al-Khoury, Racha, Lavallée-Adam, Mathieu, Faubert, Denis, Jiang, Heng, Poitras, Christian, Bouchard, Annie, Forget, Diane, Blanchette, Mathieu, Coulombe, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492713/
https://ncbi.nlm.nih.gov/pubmed/19450687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.05.005
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