p-TSA-promoted syntheses of 5H-benzo[h] thiazolo[2,3-b]quinazoline and indeno[1,2-d] thiazolo[3,2-a]pyrimidine analogs: molecular modeling and in vitro antitumor activity against hepatocellular carcinoma

In our efforts to address the rising incidence of hepatocellular carcinoma (HCC), we have made a commitment to the synthesis of novel molecules to combat Hep-G2 cells. A facile and highly efficient one-pot, multicomponent reaction has been successfully devised utilizing a p-toluenesulfonic acid (p-T...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Keshari, Amit K, Singh, Ashok K, Raj, Vinit, Rai, Amit, Trivedi, Prakruti, Ghosh, Balaram, Kumar, Umesh, Rawat, Atul, Kumar, Dinesh, Saha, Sudipta
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459977/
https://ncbi.nlm.nih.gov/pubmed/28615927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S136692
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