Severe Pulmonary Arterial Hypertension Induced by SU5416 and Ovalbumin Immunization

The combination of chronic hypoxia and treatment of rats with the vascular endothelial growth factor (VEGF) receptor blocker, SU5416, induces pulmonary angio-obliteration, resulting in severe pulmonary arterial hypertension (PAH). Inflammation is thought to contribute to the pathology of PAH. Allerg...

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Publicado en:Am J Respir Cell Mol Biol
Main Authors: Mizuno, Shiro, Farkas, Laszlo, Al Husseini, Aysar, Farkas, Daniela, Gomez-Arroyo, Jose, Kraskauskas, Donatas, Nicolls, Mark R., Cool, Carlyne D., Bogaard, Herman J., Voelkel, Norbert F.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459528/
https://ncbi.nlm.nih.gov/pubmed/22842496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0077OC
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