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Copper Deficiency Induced Emphysema Is Associated with Focal Adhesion Kinase Inactivation
BACKGROUND: Copper is an important regulator of hypoxia inducible factor 1 alpha (HIF-1α) dependent vascular endothelial growth factor (VEGF) expression, and is also required for the activity of lysyl oxidase (LOX) to effect matrix protein cross-linking. Cell detachment from the extracellular matrix...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262830/ https://ncbi.nlm.nih.gov/pubmed/22276220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030678 |
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