Copper Dependence of Angioproliferation in Pulmonary Arterial Hypertension in Rats and Humans

Obliteration of the vascular lumen by endothelial cell growth is a hallmark of many forms of severe pulmonary arterial hypertension. Copper plays a significant role in the control of endothelial cell proliferation in cancer and wound-healing. We sought to determine whether angioproliferation in rats...

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Autori principali: Bogaard, Harm J., Mizuno, Shiro, Guignabert, Christophe, Al Hussaini, Aysar A., Farkas, Daniela, Ruiter, Gerrina, Kraskauskas, Donatas, Fadel, Elie, Allegood, Jeremy C., Humbert, Marc, Noordegraaf, Anton Vonk, Spiegel, Sarah, Farkas, Laszlo, Voelkel, Norbert F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361355/
https://ncbi.nlm.nih.gov/pubmed/22162909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0296OC
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