Copper Dependence of Angioproliferation in Pulmonary Arterial Hypertension in Rats and Humans

Obliteration of the vascular lumen by endothelial cell growth is a hallmark of many forms of severe pulmonary arterial hypertension. Copper plays a significant role in the control of endothelial cell proliferation in cancer and wound-healing. We sought to determine whether angioproliferation in rats...

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Hlavní autoři: Bogaard, Harm J., Mizuno, Shiro, Guignabert, Christophe, Al Hussaini, Aysar A., Farkas, Daniela, Ruiter, Gerrina, Kraskauskas, Donatas, Fadel, Elie, Allegood, Jeremy C., Humbert, Marc, Noordegraaf, Anton Vonk, Spiegel, Sarah, Farkas, Laszlo, Voelkel, Norbert F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361355/
https://ncbi.nlm.nih.gov/pubmed/22162909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0296OC
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