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Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation

Expression of C1q, an early component of the classical complement pathway, has been shown to be induced in neurons in hippocampal slices, following accumulation of exogenous Aβ42. Microglial activation was also detected by surface marker expression and cytokine production. To determine whether C1q i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, Rong, Tenner, Andrea J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC545941/
https://ncbi.nlm.nih.gov/pubmed/15642121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-2-1
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