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Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation

Expression of C1q, an early component of the classical complement pathway, has been shown to be induced in neurons in hippocampal slices, following accumulation of exogenous Aβ42. Microglial activation was also detected by surface marker expression and cytokine production. To determine whether C1q i...

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Autors principals: Fan, Rong, Tenner, Andrea J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC545941/
https://ncbi.nlm.nih.gov/pubmed/15642121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-2-1
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