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Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation

Expression of C1q, an early component of the classical complement pathway, has been shown to be induced in neurons in hippocampal slices, following accumulation of exogenous Aβ42. Microglial activation was also detected by surface marker expression and cytokine production. To determine whether C1q i...

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Detalhes bibliográficos
Main Authors: Fan, Rong, Tenner, Andrea J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545941/
https://ncbi.nlm.nih.gov/pubmed/15642121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-2-1
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