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Anoikis Disruption of Focal Adhesion-Akt Signaling Impairs Renal Cell Carcinoma

BACKGROUND: Quinazoline-based α1-adrenoceptor antagonists suppress tumor growth by inducing apoptosis via an α1-adrenoceptor-independent action. Anoikis is a unique mode of apoptosis consequential to insufficient cell-matrix interactions. OBJECTIVE: This study investigated the apoptotic effect of no...

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發表在:Eur Urol
Main Authors: Sakamoto, Shinichi, Schwarze, Steven, Kyprianou, Natasha
格式: Artigo
語言:Inglês
出版: 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458734/
https://ncbi.nlm.nih.gov/pubmed/21269758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2010.12.038
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