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High-resolution cryo-EM proteasome structures in drug development
With the recent advances in biological structural electron microscopy (EM), protein structures can now be obtained by cryo-EM and single-particle analysis at resolutions that used to be achievable only by crystallographic or NMR methods. We have explored their application to study protein–ligand int...
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| Udgivet i: | Acta Crystallogr D Struct Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458494/ https://ncbi.nlm.nih.gov/pubmed/28580914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798317007021 |
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