Licochalcone A specifically induces cell death in glioma stem cells via mitochondrial dysfunction

Glioblastoma multiforme is the most malignant primary intrinsic brain tumor. Glioma stem cells (GSCs) are associated with chemoradiotherapy resistance and the recurrence of glioblastomas after conventional therapy. The targeting of GSCs is potentially an effective treatment for the long‐term surviva...

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Vydáno v:FEBS Open Bio
Hlavní autoři: Kuramoto, Kenta, Suzuki, Shuhei, Sakaki, Hirotsugu, Takeda, Hiroyuki, Sanomachi, Tomomi, Seino, Shizuka, Narita, Yoshitaka, Kayama, Takamasa, Kitanaka, Chifumi, Okada, Masashi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458486/
https://ncbi.nlm.nih.gov/pubmed/28593138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12226
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