Licochalcone A specifically induces cell death in glioma stem cells via mitochondrial dysfunction

Glioblastoma multiforme is the most malignant primary intrinsic brain tumor. Glioma stem cells (GSCs) are associated with chemoradiotherapy resistance and the recurrence of glioblastomas after conventional therapy. The targeting of GSCs is potentially an effective treatment for the long‐term surviva...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Kuramoto, Kenta, Suzuki, Shuhei, Sakaki, Hirotsugu, Takeda, Hiroyuki, Sanomachi, Tomomi, Seino, Shizuka, Narita, Yoshitaka, Kayama, Takamasa, Kitanaka, Chifumi, Okada, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458486/
https://ncbi.nlm.nih.gov/pubmed/28593138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12226
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