Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

Control of the cancer stem/initiating cell population is considered key to realizing the long-term survival of glioblastoma patients. Recently, we demonstrated that FOXO3 activation is sufficient to induce differentiation of glioma-initiating cells having stem-like properties and inhibit their tumor...

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Главные авторы: Sato, Atsushi, Sunayama, Jun, Okada, Masashi, Watanabe, Eriko, Seino, Shizuka, Shibuya, Keita, Suzuki, Kaori, Narita, Yoshitaka, Shibui, Soichiro, Kayama, Takamasa, Kitanaka, Chifumi
Формат: Artigo
Язык:Inglês
Опубликовано: AlphaMed Press 2012
Предметы:
Cancer Stem Cells
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659661/
https://ncbi.nlm.nih.gov/pubmed/23197693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0058
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