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The crystal structure of human DEAH-box RNA helicase 15 reveals a domain organization of the mammalian DEAH/RHA family

DEAH-box RNA helicase 15 (DHX15) plays important roles in RNA metabolism, including in splicing and in ribosome biogenesis. In addition, mammalian DHX15 also mediates the innate immune sensing of viral RNA. However, structural information on this protein is not available, although the structure of t...

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Détails bibliographiques
Publié dans:Acta Crystallogr F Struct Biol Commun
Auteurs principaux: Murakami, Karin, Nakano, Kenji, Shimizu, Toshiyuki, Ohto, Umeharu
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458392/
https://ncbi.nlm.nih.gov/pubmed/28580923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X17007336
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