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Directing oncogenic fusion genes into stem cells via an SCL enhancer

TEL-TRKC is a fusion gene generated by chromosomal translocation and encodes an activated tyrosine kinase. Uniquely, it is found in both solid tumors and leukemia. However, a single exon difference (in TEL) in TEL-TRKC fusions is associated with the two sets of cancer phenotypes. We expressed the tw...

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Hlavní autoři: Eguchi, Mariko, Eguchi-Ishimae, Minenori, Green, Anthony, Enver, Tariq, Greaves, Mel
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC545834/
https://ncbi.nlm.nih.gov/pubmed/15650051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405318102
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