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Directing oncogenic fusion genes into stem cells via an SCL enhancer
TEL-TRKC is a fusion gene generated by chromosomal translocation and encodes an activated tyrosine kinase. Uniquely, it is found in both solid tumors and leukemia. However, a single exon difference (in TEL) in TEL-TRKC fusions is associated with the two sets of cancer phenotypes. We expressed the tw...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545834/ https://ncbi.nlm.nih.gov/pubmed/15650051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405318102 |
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