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PGE(2)/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells
Prostaglandin E(2) (PGE(2)) interacts with tyrosine kinases receptor signaling in both tumor and stromal cells supporting tumor progression. Here we demonstrate that in non-small cell lung carcinoma (NSCLC) cells, A549 and GLC82, PGE(2) promotes nuclear translocation of epidermal growth factor recep...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458206/ https://ncbi.nlm.nih.gov/pubmed/28415726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16116 |
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