Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and −186 expression: Novel mechanism of VEGF modulation in prostate cancer

Prostaglandin E-2 (PGE-2) promotes tumor angiogenesis via paracrine secretion of pro-angiogenic growth factors, such as vascular endothelial growth factor (VEGF). Since miRNAs regulate several cell processes, including angiogenesis, we sought to determine whether they would influence PGE-2-induced V...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Terzuoli, Erika, Donnini, Sandra, Finetti, Federica, Nesi, Gabriella, Villari, Donata, Hanaka, Hiromi, Radmark, Olof, Giachetti, Antonio, Ziche, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190102/
https://ncbi.nlm.nih.gov/pubmed/27322147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10051
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