PGE(2)/EP(4) receptor attenuated mucosal injury via β‐arrestin1/Src/EGFR‐mediated proliferation in portal hypertensive gastropathy

BACKGROUND AND PURPOSE: Portal hypertensive gastropathy (PHG) is a serious complication of liver cirrhosis and a potential cause of bleeding in patients with cirrhosis. Suppressed mucosal epithelial proliferation is a crucial pathological characteristic of PHG. Our studies demonstrated an important...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Tan, Siwei, Chen, Xiaoliang, Xu, Minyi, Huang, Xiaoli, Liu, Huiling, Jiang, Jie, Lu, Yu, Peng, Xiaojie, Wu, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386997/
https://ncbi.nlm.nih.gov/pubmed/28213942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13752
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