Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells

Gain of functional mutations in ras occurs in more than 30% of human malignancies and in particular 90% of pancreatic cancer. Mutant ras, via activating multiple effector pathways, not only promote cell growth or survival, but also apoptosis, depending upon cell types or circumstances. In order to f...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Ganapathy, Suthakar, Peng, Bo, Shen, Ling, Yu, Tianqi, Lafontant, Jean, Li, Ping, Xiong, Rui, Makriyannis, Alexandros, Chen, Changyan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458183/
https://ncbi.nlm.nih.gov/pubmed/28415683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16047
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