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Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells
Gain of functional mutations in ras occurs in more than 30% of human malignancies and in particular 90% of pancreatic cancer. Mutant ras, via activating multiple effector pathways, not only promote cell growth or survival, but also apoptosis, depending upon cell types or circumstances. In order to f...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458183/ https://ncbi.nlm.nih.gov/pubmed/28415683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16047 |
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