Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells

Gain of functional mutations in ras occurs in more than 30% of human malignancies and in particular 90% of pancreatic cancer. Mutant ras, via activating multiple effector pathways, not only promote cell growth or survival, but also apoptosis, depending upon cell types or circumstances. In order to f...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Ganapathy, Suthakar, Peng, Bo, Shen, Ling, Yu, Tianqi, Lafontant, Jean, Li, Ping, Xiong, Rui, Makriyannis, Alexandros, Chen, Changyan
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458183/
https://ncbi.nlm.nih.gov/pubmed/28415683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16047
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