CYP2C19 variants and epoxyeicosatrienoic acids in patients with microvascular angina

BACKGROUND: Categorization as a cytochrome P450 (CYP) 2C19 poor metabolizer (PM) is reported to be an independent risk factor for cardiovascular disease. Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid by CYP2C19 epoxygenases and anti-inflammatory properties, especially in micro...

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Détails bibliographiques
Publié dans:Int J Cardiol Heart Vasc
Auteurs principaux: Akasaka, Tomonori, Sueta, Daisuke, Arima, Yuichiro, Tabata, Noriaki, Takashio, Seiji, Izumiya, Yasuhiro, Yamamoto, Eiichiro, Tsujita, Kenichi, Kojima, Sunao, Kaikita, Koichi, Kajiwara, Ayami, Morita, Kazunori, Oniki, Kentaro, Saruwatari, Junji, Nakagawa, Kazuko, Hokimoto, Seiji
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458130/
https://ncbi.nlm.nih.gov/pubmed/28616567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2017.03.001
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