CYP2C19 variants and epoxyeicosatrienoic acids in patients with microvascular angina

BACKGROUND: Categorization as a cytochrome P450 (CYP) 2C19 poor metabolizer (PM) is reported to be an independent risk factor for cardiovascular disease. Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid by CYP2C19 epoxygenases and anti-inflammatory properties, especially in micro...

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Опубликовано в: :Int J Cardiol Heart Vasc
Главные авторы: Akasaka, Tomonori, Sueta, Daisuke, Arima, Yuichiro, Tabata, Noriaki, Takashio, Seiji, Izumiya, Yasuhiro, Yamamoto, Eiichiro, Tsujita, Kenichi, Kojima, Sunao, Kaikita, Koichi, Kajiwara, Ayami, Morita, Kazunori, Oniki, Kentaro, Saruwatari, Junji, Nakagawa, Kazuko, Hokimoto, Seiji
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458130/
https://ncbi.nlm.nih.gov/pubmed/28616567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2017.03.001
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