CYP2C19 variants and epoxyeicosatrienoic acids in patients with microvascular angina

BACKGROUND: Categorization as a cytochrome P450 (CYP) 2C19 poor metabolizer (PM) is reported to be an independent risk factor for cardiovascular disease. Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid by CYP2C19 epoxygenases and anti-inflammatory properties, especially in micro...

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Detalhes bibliográficos
Publicado no:Int J Cardiol Heart Vasc
Main Authors: Akasaka, Tomonori, Sueta, Daisuke, Arima, Yuichiro, Tabata, Noriaki, Takashio, Seiji, Izumiya, Yasuhiro, Yamamoto, Eiichiro, Tsujita, Kenichi, Kojima, Sunao, Kaikita, Koichi, Kajiwara, Ayami, Morita, Kazunori, Oniki, Kentaro, Saruwatari, Junji, Nakagawa, Kazuko, Hokimoto, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458130/
https://ncbi.nlm.nih.gov/pubmed/28616567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2017.03.001
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