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How biologically relevant are interaction-based modules in protein networks?

By applying a graph-based algorithm to yeast protein-interaction networks we have extracted modular structures and show that they can be validated using information from the phylogenetic conservation of the network components. We show that the module cores, the parts with the highest intramodular co...

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Detalhes bibliográficos
Main Authors: Poyatos, Juan F, Hurst, Laurence D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545784/
https://ncbi.nlm.nih.gov/pubmed/15535869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-11-r93
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