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Biological interaction networks are conserved at the module level

BACKGROUND: Orthologous genes are highly conserved between closely related species and biological systems often utilize the same genes across different organisms. However, while sequence similarity often implies functional similarity, interaction data is not well conserved even for proteins with hig...

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Detalhes bibliográficos
Main Authors: Zinman, Guy E, Zhong, Shan, Bar-Joseph, Ziv
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212960/
https://ncbi.nlm.nih.gov/pubmed/21861884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-134
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