Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli

BACKGROUND: The chromosome of Escherichia coli is maintained in a negatively supercoiled state, and supercoiling levels are affected by growth phase and a variety of environmental stimuli. In turn, supercoiling influences local DNA structure and can affect gene expression. We used microarrays repres...

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Main Authors: Peter, Brian J, Arsuaga, Javier, Breier, Adam M, Khodursky, Arkady B, Brown, Patrick O, Cozzarelli, Nicholas R
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2004
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC545778/
https://ncbi.nlm.nih.gov/pubmed/15535863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-11-r87
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