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Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis
ABSTRACT: Bioactive lipids contribute to the pathophysiology of multiple sclerosis. Here, we show that lysophosphatidic acids (LPAs) are dysregulated in multiple sclerosis (MS) and are functionally relevant in this disease. LPAs and autotaxin, the major enzyme producing extracellular LPAs, were anal...
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Veröffentlicht in: | Acta Neuropathol Commun |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
BioMed Central
2017
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5457661/ https://ncbi.nlm.nih.gov/pubmed/28578681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0446-4 |
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