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Inhibitors of ubiquitin E3 ligase as potential new antimalarial drug leads
BACKGROUND: Protein ubiquitylation is an important post-translational regulation, which has been shown to be necessary for life cycle progression and survival of Plasmodium falciparum. Ubiquitin is a highly conserved 76 amino acid polypeptide, which attaches covalently to target proteins through com...
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Опубликовано в: : | BMC Pharmacol Toxicol |
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Главные авторы: | , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BioMed Central
2017
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5457628/ https://ncbi.nlm.nih.gov/pubmed/28577368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0147-4 |
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