The spatial distribution of exposed nuclear DNA in normal, cancer, and reverse-transformed cells.
The malignant CHO-K1 cell is reverse-transformed by cAMP, regaining the phenotype of a normal fibroblast. During this reaction, much of its DNA re-acquires sensitivity to hydrolysis by DNase I in a way characteristic of the normal fibroblast. Exposed DNA forms a rim about the nucleus in both the nor...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1990
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1697684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.17.6560 |
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