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The spatial distribution of exposed nuclear DNA in normal, cancer, and reverse-transformed cells.

The malignant CHO-K1 cell is reverse-transformed by cAMP, regaining the phenotype of a normal fibroblast. During this reaction, much of its DNA re-acquires sensitivity to hydrolysis by DNase I in a way characteristic of the normal fibroblast. Exposed DNA forms a rim about the nucleus in both the nor...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Krystosek, A, Puck, T T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54576/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1697684/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.17.6560
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