11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

We have previously demonstrated that neutrophil recruitment to the heart following myocardial infarction (MI) is enhanced in mice lacking 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that regenerates active glucocorticoid within cells from intrinsically inert metabolites. The present study aim...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Mylonas, Katie J, Turner, Neil A, Bageghni, Sumia A, Kenyon, Christopher J, White, Christopher I, McGregor, Kieran, Kimmitt, Robert A, Sulston, Richard, Kelly, Valerie, Walker, Brian R, Porter, Karen E, Chapman, Karen E, Gray, Gillian A
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457506/
https://ncbi.nlm.nih.gov/pubmed/28522730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0501
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