11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

We have previously demonstrated that neutrophil recruitment to the heart following myocardial infarction (MI) is enhanced in mice lacking 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that regenerates active glucocorticoid within cells from intrinsically inert metabolites. The present study aim...

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Dettagli Bibliografici
Pubblicato in:J Endocrinol
Autori principali: Mylonas, Katie J, Turner, Neil A, Bageghni, Sumia A, Kenyon, Christopher J, White, Christopher I, McGregor, Kieran, Kimmitt, Robert A, Sulston, Richard, Kelly, Valerie, Walker, Brian R, Porter, Karen E, Chapman, Karen E, Gray, Gillian A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bioscientifica Ltd 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457506/
https://ncbi.nlm.nih.gov/pubmed/28522730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0501
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